Characteristics of cytokine status in the pathogenesis of experimental periodontitis and immobilization stress

The aim of our study is to elucidate changes in the content pro-inflammatory interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) anti-inflammatory cytokines interleukin-10 (IL-10) blood serum guinea pigs dynamics experimental periodontitis immobilization stress.The combined pathology (experimental stress) accompanied by a pronounced progression proinflammatory group - TNF-α IL-6 against background declining functional activity IL-10 at all stages their formation (3 rd , 5 th 15 days) with an advantage on day experiment. data obtained indicate imbalance pro- impaired cytokinogenesis, which important for pathogenesis this pathology.